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It’s also worth noting that even if alternatives superior to agar were found, scientists are reluctant to abandon established protocols (even when microbiologists do use other jellies, they often still add agar to the mix, for example, to increase the gel strength of the solid media). As agar has been the standard gelling agent in microbiology for around 150 years, an enormous infrastructure of standardized methods, reference values, and quality control procedures has emerged around its specific properties. Switching to a different medium (even a superior one) means results may not be directly comparable to decades of published literature or to other laboratories’ findings.

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We’ll apply a selective screening process on applications. At this stage, we’re primarily going to look for signals that worked well for us in the past & what we outlined in the “What we are looking for” section.

Dynamic antigen expression and cytotoxic T cell resistance in HIV reservoir clones

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